It Causes a Major Reduction in Blood Sugar Levels Berberine May Help You Lose Weight It Lowers Cholesterol and May Reduce Your Risk of Heart Disease Other Health Benefits of Berberine: Depression: Rat studies show that it may help fight depression Cancer: Test tube and animal studies have shown that it can reduce the growth and spread of various different types of cancer Antioxidant and anti-inflammatory: It has been shown to have potent antioxidant and anti-inflammatory effects in some studies Infections: It has been shown to fight harmful microorganisms, including bacteria, viruses, fungi, and parasites Fatty liver: It can reduce fat build-up in the liver, which should help protect against non-alcoholic fatty liver disease (NAFLD) Heart failure: One study showed that it drastically improved symptoms and reduced risk of death in heart failure patients